Ginger is primarily known for its antiviral properties. The root of this plant is not only used in cuisine but is also added as a spice to dishes or beverages. Scientists from Japan have studied an Indonesian variety of ginger and demonstrated that the extract from the root of this plant effectively inhibits the development of cancer cells. They successfully identified the complete mechanism of the compound's action, along with its active anti-cancer component.

A team from Osaka City University examined the properties of Kaempferia galanga L, a tropical plant from the ginger family that grows in Indonesia and several other Southeast Asian countries. The extract from the root of Kaempferia galanga L is known for its antioxidant and anti-inflammatory properties. In their recent study, scientists showcased the benefits of this plant compound in combating cancer.

In preclinical models, it was observed that the primary active ingredient in the plant, ethyl p-methoxycinnamate (EMC), significantly inhibits the growth of cancer cells. Further experiments revealed that EMC hinders the proliferation of cancer cells by regulating the expression of cyclin D1 and p21 proteins, as well as the mitochondrial transcription factor A (TFAM), associated with cancer cell proliferation.

"The results confirm the anti-cancer action of Kaempferia galanga L and its main active component, EMC. Perhaps TFAM will become a new biomarker for anti-cancer activity," comments Akiko Kojima, the lead author.

Currently, scientists are progressing through the preclinical phase of experiments on models of various types of cancers. Confirmation of the versatility and effectiveness of this new approach in cancer treatment is essential. If successful, researchers may develop cancer-targeting drugs without the toxic side effects associated with the primary method of cancer treatment, chemotherapy.